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药明康德AI · AI for Science

TOX-生物分析研发高级研究员(质谱方向)

上海 社招 · 全职 分析类 研究 / 科学

职位描述

We are seeking a Bio-analytical R&D Scientist (LC-MS) to lead the design, development, and optimization of cutting-edge analytical methods. The ideal candidate will hold a Ph.D. degree and possess deep, hands-on expertise in targeted LC-MS (MRM) and advanced sample preparation techniques. In this role, you will act as a key technical expert, driving projects from conception to execution while collaborating externally. Key Responsibilities: - Method Development: Independently design, develop, optimize, and troubleshoot sample preparation workflows and targeted LC-MS/MS (MRM) methods for the quantification of complex therapeutics (e.g., small molecules, peptides, oligos, antibodies) or biomarkers in various biological matrices. - Innovation & Automation: Continually evaluate and integrate new analytical technologies. (If applicable: spearhead the integration of programing/laboratory automation to increase high-throughput capabilities - Scientific Communication: Author, review, and finalize scientific documents, including project proposal, method development reports, conference presentations, journal articles, and patents if applicable. Present findings and insights to internal stakeholders and high-level management. - Project Leadership: Take full ownership of analytical R&D projects, acting with a high degree of independence to deliver high-quality, reproducible data.

任职要求

Job requirements: - Ph.D. in Analytical Chemistry, Biochemistry, Pharmacokinetics, Pharmaceutical Sciences, or a closely related discipline. - Professional proficiency in English (both verbal and written) is an absolute must. Highly capable of authoring technical reports and leading scientific discussions in English. - Significant, hands-on experience in targeted LC-MS/MS method development, with demonstrated expertise in complex sample preparation strategies, including but not limited to SPE, LLE, Immunocapture, and Ultrafiltration, etc. - Self-driven, highly independent, and proactive. Must demonstrate the ability to navigate ambiguity and solve complex analytical challenges with minimal supervision. - Hands-on experience with laboratory automation and automated liquid handling platforms (e.g., Hamilton, Tecan) is preferred - Programming Skills: Knowledge of programming languages (e.g., Python, R) or data analysis/scripting tools to streamline data processing, visualization, or laboratory workflows is preferred. - Prior working experience in a regulated GxP environment and familiarity with regulatory guidelines for bioanalysis is a plus.
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